TARP syndrome is rare genetic condition (with fewer than 50 known individuals around the world) that can cause developmental delays and variable health issues affecting different parts of the body including commonly the heart and sometimes also the lungs and kidneys. It is an X-linked condition caused by changes to the RBM10 gene, which only affects males who inherit a single X chromosome with a change to the RBM10 gene. Due to this, the mothers and sisters of individuals may choose to be tested for the identified change to the RBM10 gene in order to assess the recurrence risk for the condition in their children (50% for each son if a women is a carrier). It will be important to meet with a genetics professional such as a genetic counselor if you are considering such testing.
RBM10