TPP2

Clinical Characteristics for Families

The clinical features or TPP2 deficiency includes:

•    Infection predisposition
o    Recurrent upper and lower tract respiratory infections: infection of the ears, sinuses of the skull or lung.
o    Severe viral infections

•    Autoimmune disorder predisposition
o    Low levels of blood cells
o    A broad range of non-specific autoimmune diseases involving liver, skin, thyroid, blood vessels and brain.

•    Mild to moderate developmental delay/intellectual deficiency

•    Some behavior troubles such as hyperactivity and attention deficit