CHD8

Publications

Bernier R, et al. Disruptive CHD8 mutations define a subtype of autism early in development. Cell, 2014;158:263-76. PMID: 24998929.

O’Roak BJ, et al. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature. 2012;485:246-50. PMID: 22495309.

O’Roak BJ, et al. Multiplex Targeted Sequencing Identifies Genes Recurrently Disrupted in Autism Spectrum Disorders. Science. 2012;338:1619-1622. PMID: 23160955.

McCarthy SE, et al. De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability. Molecular Psychiatry. 2014;19:652-658. PMID: 24776741.

Wilkinson B, et al. The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes. Transl Psychiatry. 2015;5:e568. PMID: 25989142.

Iossifov I, et al. Low load for disruptive mutations in autism genes and their biased transmission. Proc Natl Acad Sci USA. 2015;112(41):E5600-7. PMID: 26401017.

Cotney J, et al. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Nat Commun. 2015;6:6404. PMID: 25752243.

Stolerman ES, et al. CHD8 intragenic deletion associated with autism spectrum disorder. Eur J Med Genet. 2016;59(4):189-94. PMID: 26921529.

Stessman HA, et al. Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases. Nat Genet. 2017;49(4):515-526. PMID: 28191889.